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Histamine, Mast Cells & Hormones
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Have you noticed that symptoms like allergies, headaches, gut flares, or anxiety often don’t appear randomly, but instead seem to follow the rhythm of your menstrual cycle?

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Spot Patterns, and Reduce Flares

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(Days 1–5)

  • Estrogen ↓, Progesterone ↓

  • Mast cell instability → itching, hives, food reactions

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Follicular (Days 6–13)

  • Estrogen ↑

  • Low blood volume → dizziness, fatigue, palpitations

  • Histamine flares possible

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Ovulation (~Day 14)

  • Estrogen peak, Progesterone low

  • Histamine surge → allergies, headaches, gut issues, anxiety

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Luteal (Days 15–28)

  • Progesterone ↑, Estrogen moderate

  • Protective for some, but hypermobility → joint pain/instability

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Premenstrual (Late Luteal, Days 24–28)

  • Progesterone ↓, Estrogen fluctuates

  • Prostaglandins + histamine → cramps, migraines, gut flares

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By tracking your cycle, you can uncover patterns in your symptoms, gain insight into your body’s unique responses, and take proactive steps to support yourself before flare-ups occur, while working on the underlying causes via our Metabolic Reboot

 

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